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1432 : Vesicular Stomatitis Virus (VSV) Engineered to Express CD19 Stimulates Anti-CD19 Chimeric Antigen Receptor Modified T Cells and Promotes Their Anti-Tumor Effects

Researchers

Presenter

  • Reona Sakemura

Principal Investigators

  • Sydney B. Crotts

  • Linh Pham

  • Elizabeth L. Siegler

  • Michelle J. Cox

  • Erin E. Tapper

  • Mehrdad Hefazi

  • Claudia Manriquez Roman

  • Kendall J. Schick

  • Ismail Can

  • Evandro D. Bezerra

  • Lionel Kankeu Fonkoua

  • Paulina Horvei

  • Michael W. Ruff

  • Susan L. Slager

  • Sameer A. Parikh

  • Neil E. Kay

  • Kah-Whye Peng

  • Stephen J. Russell

  • Saad S. Kenderian

Medical Centers

  • T-Cell Engineering Program, Mayo Clinic, Rochester, MN

  • Division of Medical Oncology, Mayo Clinic, Rochester, MN

  • Department of Internal Medicine, Mayo Clinic, Rochester, MN

  • Clinical and Translational Science Track, Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN

  • Department of Oncology, Mayo Clinic, Rochester, MN

  • Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA

  • Bioinformatics and Computation Biology, University of Minnesota Graduate School, Rochester, MN

  • Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN

  • Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA

  • Department of Oncology, Mayo Clinic, Rochester, MN

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Acute myelocytic leukemia

  • B cell lymphomas

  • Solid malignancies

Biomarkers

  • Peripheral blood mononuclear cell

  • Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • Randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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