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1095 : Outcomes of Patients with CRLF2-Overexpressing Acute Lymphoblastic Leukemia without Down Syndrome: A Report from the Children’s Oncology Group

Researchers

Presenter

  • Sarah K Tasian

Principal Investigators

  • Meenakshi Devidas

  • Kathryn G Roberts

  • Richard C Harvey

  • I-Ming L Chen

  • Andrew J Carroll

  • Nyla A Heerema

  • Shalini C Reshmi

  • Julie M Gastier-Foster

  • Michael J Borowitz

  • Brent L Wood

  • Charles G Mullighan

  • Cheryl L Willman

  • Kelly W Maloney

  • Eric C Larsen

  • Anne L Angiolillo

  • Reuven J Schore

  • Michael J Burke

  • Wanda L Salzer

  • Naomi J Winick

  • William L. Carroll

  • Stephen P Hunger

  • Elizabeth A. Raetz

  • Karen R Rabin

  • Mignon L. Loh

Medical Centers

  • Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

  • Center for Childhood Cancer Research, Childrens Hospital of Philadelphia, Philadelphia, PA

  • Department of Biostatistics, University of Florida, Gainesville, FL

  • Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • University of New Mexico School of Medicine, Albuquerque, NM

  • Department of Pathology, University of New Mexico Cancer Rsch Facility, Albuquerque, NM

  • Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL

  • Department of Pathology, The Ohio State University, Columbus, OH

  • Nationwide Children's Hospital, Columbus, OH

  • Department of Pediatrics, Division of Neonatology, Baylor College of Medicine, Texas Childrens Hospital, Houston, TX

  • Department of Oncology, Johns Hopkins University, Baltimore, MD

  • Department of Laboratory Medicine, University of Washington, Seattle, WA

  • Department of Pathology, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM

  • Department of Pediatrics, Division of Pediatric Hematology/Oncology/BMT, Children’s Hospital Colorado and University of Colorado School of Medicine, Aurora, CO

  • Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME

  • Children’s National Health System/George Washington University SMHS, Washington, DC

  • Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.

  • U.S. Army Medical Research and Materiel Command, Fort Detrick, MD

  • Department of Internal Medicine, Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX

  • Division of Pediatric Hematology and Oncology, Perlmutter Cancer Center, NYU Cancer Institute, New York, NY

  • Department of Pediatrics, Division of Oncology and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

  • New York University Medical Center, New York City, NY

  • Baylor College of Medicine/Texas Childrens Cancer Center, Houston, TX.

  • Department of Pediatrics, Division of Hematology-Oncology, University of California, San Francisco and Benioff Children's Hospital, San Francisco, CA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Down syndrome

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • N/A

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • III

Study Id's

  • NCT0240717

  • NCT02723994

  • NCT02883049

  • NCT03571321

Sponsors

  • N/A

Result

  • N/A

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