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1094 : Outcomes of Patients with Down Syndrome and CRLF2-Overexpressing Acute Lymphoblastic Leukemia (ALL): A Report from the Children’s Oncology Group (COG)

Researchers

Presenter

  • Karen R Rabin

Principal Investigators

  • Zhiguo Chen

  • Yunfeng Dai

  • Sarah K Tasian

  • Johann K Hitzler

  • Kathryn G Roberts

  • Andrew J Carroll

  • Nyla A Heerema

  • Michael J Borowitz

  • Brent L Wood

  • Charles G Mullighan

  • Richard C Harvey

  • I-Ming L Chen

  • Cheryl L Willman

  • Shalini C Reshmi

  • Julie M Gastier-Foster

  • Kelly W Maloney

  • Eric C Larsen

  • Reuven J Schore

  • Michael J Burke

  • Wanda L Salzer

  • Naomi J Winick

  • William L. Carroll

  • Elizabeth A. Raetz

  • Anne Angiolillo

  • Mignon L. Loh

  • Stephen P Hunger

Medical Centers

  • Baylor College of Medicine/Texas Childrens Cancer Center, Houston, TX.

  • Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX

  • Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN

  • Dept of Biostatistics, Colleges of Medicine, Public Health & Health Professions, University of Florida, Gainsville, FL

  • Department of Biostatistics, University of Florida, Gainesville, FL

  • Center for Childhood Cancer Research, Childrens Hospital of Philadelphia, Philadelphia, PA

  • Hospital for Sick Children, Toronto, ON, Canada

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL

  • Department of Pathology, The Ohio State University, Columbus, OH

  • Department of Oncology, Johns Hopkins University, Baltimore, MD

  • Department of Laboratory Medicine, University of Washington, Seattle, WA

  • University of New Mexico School of Medicine, Albuquerque, NM

  • Department of Pathology, University of New Mexico Cancer Rsch Facility, Albuquerque, NM

  • Department of Pathology, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM

  • Nationwide Children's Hospital, Columbus, OH

  • Department of Pediatrics, Division of Neonatology, Baylor College of Medicine, Texas Childrens Hospital, Houston, TX

  • Department of Pediatrics, Division of Pediatric Hematology/Oncology/BMT, Children’s Hospital Colorado and University of Colorado School of Medicine, Aurora, CO

  • Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME

  • Children's Natl Medcl Ctr, Washington, DC

  • Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.

  • U.S. Army Medical Research and Materiel Command, Fort Detrick, MD

  • Department of Pediatrics, Division of Pediatric Hematology/Oncology, UT Southwestern, Simmons Cancer Center, and Perlmutter Cancer Center, Dallas, TX

  • Division of Pediatric Hematology and Oncology, Perlmutter Cancer Center, NYU Cancer Institute, New York, NY

  • Stephen D. Hassenfeld Children's Center for Cancer and Blood Disorders, New York, NY

  • Children's Natl Medcl Ctr, Washington, DC

  • Department of Pediatrics, Division of Hematology-Oncology, University of California, San Francisco and Benioff Children's Hospital, San Francisco, CA

  • Department of Pediatrics, Division of Oncology and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Down syndrome

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Immunoglobulin heavy-chain variable region gene

  • Janus kinase

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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