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1090 : Enhanced Risk Stratification of 21,178 Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia (ALL) Incorporating White Blood Count (WBC), Age, and Minimal Residual Disease (MRD) at Day 8 and 29 As Continuous Variables: A Children’s Oncology Group (COG) Report

Researchers

Presenter

  • Mignon L. Loh

Principal Investigators

  • Michael J Borowitz

  • Karen R Rabin

  • Patrick A Zweidler-McKay

  • Kelly W Maloney

  • Leonard A. Mattano

  • Eric C Larsen

  • Anne L Angiolillo

  • Reuven J Schore

  • Michael J Burke

  • Wanda L Salzer

  • Brent L Wood

  • Andrew J Carroll

  • Nyla A Heerema

  • Shalini C Reshmi

  • Julie M Gastier-Foster

  • Richard C Harvey

  • I-Ming L Chen

  • Cheryl L Willman

  • Naomi J Winick

  • William Carroll

  • Stephen P Hunger

  • Elizabeth A. Raetz

  • Meenakshi Devidas

  • John Kairalla

  • Kathryn G Roberts

  • Charles G Mullighan

Medical Centers

  • UCSF Benioff Children’s Hospital and the Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA

  • Department of Biostatistics, University of Florida, Gainesville, FL

  • Department of Oncology, Johns Hopkins University, Baltimore, MD

  • Baylor College of Medicine/Texas Childrens Cancer Center, Houston, TX.

  • ImmunoGen, Lincoln, MA

  • Department of Pediatrics, Division of Pediatric Hematology/Oncology/BMT, Children’s Hospital Colorado and University of Colorado School of Medicine, Aurora, CO

  • HARP Pharma Consulting, LLC, Mystic, CT

  • Department of Pediatrics, Maine Children's Cancer Program, Scarborough, ME

  • Children’s National Health System/George Washington University SMHS, Washington, DC

  • Children's Natl Medcl Ctr, Washington, DC

  • Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.

  • U.S. Army Medical Research and Materiel Command, Fort Detrick, MD

  • Department of Laboratory Medicine, University of Washington, Seattle, WA

  • Department of Laboratory Medicine, University of Washington, Seattle, WA

  • Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL

  • Department of Pathology, The Ohio State University, Columbus, OH

  • Nationwide Children's Hospital, Columbus, OH

  • Department of Pediatrics, Division of Neonatology, Baylor College of Medicine, Texas Childrens Hospital, Houston, TX

  • University of New Mexico School of Medicine, Albuquerque, NM

  • Department of Pathology, University of New Mexico Cancer Rsch Facility, Albuquerque, NM

  • Department of Pathology, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM

  • Department of Pediatrics, Division of Pediatric Hematology/Oncology, UT Southwestern, Simmons Cancer Center, and Perlmutter Cancer Center, Dallas, TX

  • Department of Pediatrics, Perlmutter Cancer Center,, New York University Medical Center, New York, NY

  • Department of Pediatrics, Division of Oncology and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

  • New York University Medical Center, New York City, NY

  • Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN

  • Dept of Biostatistics, Colleges of Medicine, Public Health & Health Professions, University of Florida, Gainsville, FL

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Down syndrome

  • Solid malignancies

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • ETV6-RUNX1

  • White Blood Cell

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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