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790 : Anti-Inflammatory Activities of Sulfated Non-Anticoagulant Heparin Derivative Beyond Its Anti-Sickling and Anti-Selectin for the Effective Management of Sickle Cell Disease

Researchers

Presenter

  • Noureldien Darwish

Principal Investigators

  • Osheiza Abdulmalik

  • Shaker A Mousa

Medical Centers

  • The Pharmaceutical Research Institute, ACPHS, Albany, NY

  • The Children's Hosp. of Phila., Philadelphia, PA

  • The Pharmaceutical Research Institute at ACPHS, Renssealaer, NY

  • Hematology/Vascular, Vascular Vision Pharmaceuticals Co., Rensselaer, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Sickle cell anemia

  • Venous thrombosis

Biomarkers

  • C-C Motif Chemokine Ligand 2

  • Colony stimulating factor 1

  • Interferon-gamma

  • Interleukin 1 beta

  • Interleukin 10

  • Interleukin 6

  • Stearoyl-CoA desaturase

  • Vascular endothelial growth factor A

  • Red Blood Cells

Drug/Treatment

  • Evithrom

  • Heparin

  • GBT440

  • Interferon Gamma

  • IFN-lambda

  • Interleukin-10

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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