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393 : Primary results of EV-301: A phase III trial of enfortumab vedotin versus chemotherapy in patients with previously treated locally advanced or metastatic urothelial carcinoma.

Researchers

Presenter

  • Thomas Powles

Principal Investigators

  • Jonathan E. Rosenberg

  • Guru Sonpavde

  • Yohann Loriot

  • Ignacio Duran

  • Jae-Lyun Lee

  • Nobuaki Matsubara

  • Christof Vulsteke

  • Chunzhang Wu

  • Mary S. Campbell

  • Maria Matsangou

  • Daniel Peter Petrylak

Medical Centers

  • Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

  • Memorial Sloan Kettering Cancer Center, Port Washington, NY

  • Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA

  • Department of Cancer Medicine, Institut Gustave Roussy, Paris-Sud University, Villejuif, France

  • Department of Medical Oncology, Hospital Universitario Marqués de Valdecilla, Cantabria, Spain

  • Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

  • Division of Breast and Medical Oncology, National Cancer Center Hospital East, Chiba, Japan

  • Center for Oncological Research (CORE), University of Antwerp, Integrated Cancer Center Ghent, Ghent, Belgium

  • Astellas Pharma, Inc., Northbrook, IL

  • Seattle Genetics, Bothell, WA

  • Astellas Pharma, Inc., Northbrook, IL

  • Yale University School of Medicine, New Haven, CT

Locations

  • United Kingdom

  • United States

  • France

  • Spain

  • Republic of South Korea

  • Japan

  • Belgium

Companies

  • Astellas Pharma Inc.

  • Seattle Genetics, In

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Urology

Disease

  • Advanced Urothelial Carcinoma

Biomarkers

  • Programmed cell death protein 1

Drug/Treatment

  • Enfortumab vedotin

  • Paclitaxel

  • vinflunine

  • Docetaxel

Outcome

  • N/A

Study Design

  • Randomized

  • Open Label

Phase

  • III

Study Id's

  • NCT03474107

Sponsors

  • N/A

Result

  • N/A

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