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LB-141 : Increased epigenetic plasticity and tumor heterogeneity predict resistance to CD19 CAR T cell therapy in pre-treatment pediatric acute lymphoblastic leukemia

Researchers

Presenter

  • Katherine E. Masih

Principal Investigators

  • David Milewski

  • Berkley E. Gryder

  • Rebecca Gardner

  • Ashley L. Wilson

  • Benjamin Z. Stanton

  • Young K. Song

  • Chaoyu Wang

  • Xinyu Wen

  • Serifat Adebola

  • Zachary Rae

  • Adam Cheuk

  • Justin Lack

  • Gregoire Altan-Bonnet

  • Michael Kelly

  • Jun Wei

  • Michael Jensen

  • Rimas J. Orentas

Medical Centers

  • National Cancer Institute, Bethesda, MD

  • Seattle Childrens Hospital, Seattle, WA

  • Seattle Children's Research Institute, Seattle, WA

  • Nationwide Children's Hospital, Columbus, OH

  • National Institute of Allergy and Infectious Diseases, Bethesda, MD

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Cluster of Differentiation 19

  • Coxsackie Virus And Adenovirus Receptor

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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