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PB1983 : The R398w Gata-2 Variant Negatively Regulates E-Nos Activity: Possible Role in GATA2 Deficiency-associated Thrombosis

Researchers

Presenter

  • G. Purgatorio

Principal Investigators

  • V. Di Battista

  • E. Piselli

  • G. Guglielmini

  • F. Pellanera

  • C. Matteucci

  • E. Falcinelli

  • L. Bury

  • C. Mecucci

  • P. Gresele

Medical Centers

  • University of Perugia, Section of Internal and Vascular Medicine, Perugia, Italy

  • University of Perugia, Department of Medicine, Hematology and BMTU, Perugia, Italy

Locations

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

Disease

  • Venous thrombosis

Biomarkers

  • Endothelial cell nitric oxide synthase

  • GATA-binding protein 2

Drug/Treatment

  • Arginine hydrochloride

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A