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PB1272 : Pharmacokinetic-Pharmacodynamic Relationship between Dabigatran Plasma Concentrations and Coagulation Laboratory Parameters in Paediatric Patients with Venous Thromboembolism

Researchers

Presenter

  • L. Mitchell

Principal Investigators

  • D. Roeshammar

  • F. Huang

  • M. Albisetti

  • L. Brandao

  • L. Bomgaars

  • E. Chalmers

  • J. Halton

  • M. Luciani

  • D. Joseph

  • I. Tartakovsky

  • S. Gropper

  • P. Reilly

  • M. Brueckmann

  • J. Stangier

Medical Centers

  • Pharmetheus,Uppsala,Sweden

  • Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, United States

  • University Children's Hospital, Hematology Department, Zürich, Switzerland

  • Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

  • Texas Children's Cancer Center, Baylor College of Medicine, Department of Pediatrics, Houston, United States

  • Royal Hospital for Sick Children, Glasgow, United Kingdom

  • Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada,

  • Pediatric Hospital Bambino Gesù, Pediatric Hematology/Oncology, Rome, Italy

  • Therapeutic Area Cardiovascular Medicine, Boehringer Ingelheim International GmbH, Ingelheim, Germany

  • Therapeutic Area Cardiovascular Medicine, Boehringer Ingelheim International GmbH, Ingelheim, Germany

  • Therapeutic Area Cardiovascular Medicine, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, United States

  • Boehringer Ingelheim Pharma GmbH and Co. KG, Biberach, Germany

Locations

  • Canada

  • Sweden

  • United States

  • Switzerland

  • United Kingdom

  • Italy

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

Disease

  • Venous thrombosis

Biomarkers

  • N/A

Drug/Treatment

  • Pradax

Outcome

  • N/A

Study Design

  • Pharmacokinetics

  • Pharmacodynamics

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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