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PB2368 : Lysophosphatidic Acid Promotes Thrombus Stability by Inducing Rapid Formation of Neutrophil Extracellular Traps via a Peptidylarginine Deiminase 4-Dependent Pathway: A New Mechanism of Thrombosis

Researchers

Presenter

  • R. Peng

Principal Investigators

  • T. Li

  • F. Wang

  • L. Hua

  • S. Liu

  • J. Pei

  • Z. Han

  • S. Pei

  • Z. Zhao

  • X. Jiang

  • X. Chen

Medical Centers

  • State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Centre for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  • Institute of Biophysics, Chinese Academy of Science, Beijing, China

  • Key Laboratory of Pulmonary Vascular Medicine, Peking Union Medical College Hospital, Chinese Academy Medical Sciences., Department of Cardiology, Beijing, China

Locations

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

Disease

  • Pulmonary embolism

  • Venous thrombosis

Biomarkers

  • Apurinic/Apyrimidinic Endodeoxyribonuclease 1

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A