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BSH2020‐OR‐042 : Gain of function variant of prothrombin (p.R541W) causes dominant heritable thrombosis and is associated with antithrombin resistance

Researchers

Presenter

  • S. Sivapalaratnam

Principal Investigators

  • V. Muczynski

  • J. Collins

  • J. Pasi

  • K. Downes

  • A. Nathwani

  • K. Gomez

Medical Centers

  • Haematology, University of Cambridge, Cambridge

  • Centre for Immunobiology, QMUL

  • Haemophilia Centre, Barts and The London, London

  • Clinical Genetics, Addenbrookes Hospital, Cambridge

  • Haemophilia Centre, Royal Free Hospital, London, UK

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

Disease

  • Venous thrombosis

Biomarkers

  • Alpha-tubulin N-acetyltransferase 1

  • Insulin-like growth factor 1 receptor

Drug/Treatment

  • Protein C

  • Arginine hydrochloride

  • Evithrom

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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