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: MINIMAL RESIDUAL DISEASE, CLINICAL OUTCOME, AND THE EFFECT OF IKZF1 DELETIONS IN PEDIATRIC DOWN SYNDROME ACUTE LYMPHOBLASTIC LEUKEMIA: AN INTERNATIONAL MATCHED PONTE DI LEGNO CASE-CONTROL STUDY

Researchers

Presenter

  • Naomi Michels

Principal Investigators

  • Judith M. Boer

  • Amir Enshaei

  • Rosemary Sutton

  • Mats Heyman

  • Marta Fiocco

  • Hester A. De Groot-Kruseman

  • Vincent H.J. van der Velden

  • Gisela Barbany

  • Ajay Vora

  • Toby Trahair

  • Luciano Dalla-Pozza

  • Rob Pieters

  • Kjeld Schmiegelow

  • Anthony V. Moorman

  • Michel C. Zwaan

  • Monique L. Den Boer

Medical Centers

  • Princess Maxima Center for Pediatric Oncology,Utrecht,Netherlands;Oncode Institute,Utrecht,Netherlands

  • Leukemia Research Cytogenetics Group, Translational and Clinical Research Institute, Newcastle University, Newcastle-upon-Tyne, United Kingdom

  • School of Women and Children's Health,UNSW Medicine,Randwick,Australia;Children's Cancer Institute,Lowy Cancer Research Centre, UNSW,Sydney,Australia

  • Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

  • Princess Máxima Center for Pediatric Oncology,Utrecht,Netherlands;Mathematical Institute,Leiden University,Leiden,Netherlands;Department of Biomedical Data Sciences, Medical Statistics Section,Leiden University Medical Center,Leiden,Netherlands

  • Princess Máxima Center for Pediatric Oncology,Utrecht,Netherlands;Dutch Childhood Oncology Group,Utrecht,Netherlands

  • Department of Immunology, Erasmus Medical Center, Rotterdam, Netherlands

  • Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Oman

  • Department of Pediatric Anesthesiology, Great Ormond Street Hospital,NHS, London, United Kingdom

  • School of Women and Children's Health,UNSW Medicine,Randwick,Australia;Kids Cancer Centre,Sydney Children's Hospital,Randwick,Australia

  • Cancer Centre for Children, The Children's Hospital at Westmead, Westmead, Australia

  • Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Copenhagen, Denmark

  • Princess Máxima Center for Pediatric Oncology,Utrecht,Netherlands;Oncode Institute,Utrecht,Netherlands;Department of Pediatric Oncology/Hematology,Erasmus MC-Sophia Children's Hospital,Rotterdam,Netherlands

  • Princess Máxima Center for Pediatric Oncology,Utrecht,Netherlands;Oncode Institute,Utrecht,Netherlands;Department of Pediatric Oncology/Hematology,Erasmus MC-Sophia Children's Hospital,Rotterdam,Netherlands

Locations

  • Netherlands

  • United Kingdom

  • Australia

  • Sweden

  • Denmark

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Down syndrome

Biomarkers

  • N/A

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • Multinational

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A