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: DEFINITION AND PROGNOSTIC IMPACT OF PH-LIKE AND IKZF1-PLUS FEATURES IN CHILDREN WITH DOWN SYNDROME ACUTE LYMPHOBLASTIC LEUKEMIA

Researchers

Presenter

  • Chiara Palmi

Principal Investigators

  • Stefanie Junk

  • Grazia Fazio

  • Daniela Silvestri

  • Marketa Zaliova

  • Andrea Grioni

  • Martin Stanulla

  • Anja Moericke

  • Martin Zimmermann

  • Martin Schrappe

  • Barbara Buldini

  • Luca Lo Nigro

  • Valentino Conter

  • Maria Grazia Valsecchi

  • Andrea Biondi

  • Geertruy te Kronnie

  • Gunnar Cario

  • Giovanni Cazzaniga

Medical Centers

  • Centro Ricerca Tettamanti,Fondazione Tettamanti,Monza,Italy

  • Oncoematologia Pediatrica,Istituto di Ricerca Pediatrica - Fondazione Città della Speranza ONLUS,Padova,Italy

  • Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany

  • Centro Operativo di Ricerca Statistica, Fondazione Tettamanti, Monza, Italy

  • Paediatric Haematology and Oncology,Hospital Motol - Charles University,Prague,Czech Republic

  • CEITEC,Brno,Czech Republic;Centro Ricerca Tettamanti,Fondazione Tettamanti,Monza,Italy

  • Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany

  • Pediatrics,Christian-Albrechts-University and University Medical Center Schleswig-Holstein,Kiel,Germany

  • Dip. della Salute della Donna e del Bambino,Università degli Studi di Padova,Padova,Italy

  • Pediatric Hematology and Oncology,Azienda Policlinico,Catania,Italy

  • Pediatric Dep, University of Milan-Bicocca, Fondazione MBBM, Monza, Italy

  • Centro Operativo di Ricerca Statistica,Fondazione Tettamanti,Monza,Italy;Statistics,University of Milan Bicocca,Monza,Italy

  • Pediatrics,Christian-Albrechts-University and University Medical Center Schleswig-Holstein,Kiel,Germany

  • Genetics,University of Milan Bicocca,Monza,Italy;Centro Ricerca Tettamanti,Fondazione Tettamanti,Monza,Italy

Locations

  • Italy

  • Germany

  • Czech Republic

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Down syndrome

Biomarkers

  • Paired box 5

  • Cyclin Dependent Kinase Inhibitor 2A

  • Cyclin Dependent Kinase Inhibitor 2B

  • ETS transcription factor ERG

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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