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: HYDROXYCHLOROQUINE SIGNIFICANTLY REDUCES SERUM MARKERS OF ENDOTHELIAL INJURY AND NEMO VIDEOCAPILLAROSCOPY SCORE IN SYSTEMIC SCLEROSIS: A 3-MONTHS PROSPECTIVE OBSERVATIONAL STUDY

Researchers

Presenter

  • Fabio Basta

Principal Investigators

  • Rosaria Irace

  • Alessia Borgia

  • Valentina Messiniti

  • Antonella Riccardi

  • Gabriele Valentini

  • Antonella Afeltra

Medical Centers

  • Università degli Studi della Campania “Luigi Vanvitelli”, Division of Rheumatology, Department of Precision Medicine, Napoli, Italy

  • Università Campus Bio-Medico di Roma, Unit of Allergology, Immunology and Rheumatology, Roma, Italy

Locations

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

  • Cardiovascular (CVS)

  • Autoimmune (AI)

  • Pulmonary/Respiratory Diseases

Disease

  • N/A

Biomarkers

  • Asymmetric Dimethylarginine

  • Endothelin-1

  • E-selectin

  • Vascular cell adhesion molecule 1

  • Vascular endothelial growth factor A

Drug/Treatment

  • Hydroxychloroquine

  • endothelin-1

  • Arginine hydrochloride

Outcome

  • N/A

Study Design

  • Observational

  • Prospective

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • Merck Sharp & Dohme (MSD)

Result

  • N/A

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