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: The European Vasculitis Society 2016 Meeting Report

Researchers

Presenter

  • Ingeborg M. Bajema

Principal Investigators

  • Alina Casian

  • Maria C. Cid

  • Elena Csernok

  • Emma van Daalen

  • Lorraine Harper

  • Thomas Hauser

  • Mark A. Little

  • Raashid A. Luqmani

  • Alfred Mahr

  • Cristina Ponte

  • Alan Salama

  • Mrten Segelmark

  • Kazuo Suzuki

  • Jan Sznajd

  • Y.K. Onno Teng

  • Augusto Vaglio

  • Kerstin Westman

  • David Jayne

Medical Centers

  • Department of Urology, Leiden Unviersity Medical Center, Leiden, Netherlands

  • QueenÂ’s Hospital, Romford, London, UK

  • Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clinic University of Barcelona, Institut -Investigacions Biomediques August Pi i Sunyer IDIBAPS, Barcelona, Spain

  • Medius Klinik Kirchheim/Vaskulitiszentrum Süd Akademisches Lehrkrankenhaus der Universität Tübingen, Kirchheim unter Teck, Tübingen, Germany

  • Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK

  • Immunologie-Zentrum Zurich, Zurich, Switzerland

  • Trinity Health Kidney Centre, Tallaght Hospital, Dublin, Ireland

  • NDORMS, Rheumatology Department, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

  • Hopital Cochin, Paris, France

  • Rheumatology Research Unit, Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, and Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisbon, Portugal

  • Centre of Gastroenterology, Royal Free Hospital, London, United Kingdom

  • Department of Medical and Health Sciences and Department of Nephrology, Linköping University, Linköping, Sweden

  • Asia International Institute of Infectious Disease Control, Teikyo University, Tokyo, Japan

  • Raigmore Hospital, Inverness, University of Aberdeen, Aberdeen, UK

  • Clinic for Lupus, Vasculitis and Complement-mediated diseases, Department of Nephrology, Leiden University Medical Center, Leiden, the Netherlands

  • Nephrology Unit, University Hospital, Parma, Italy

  • Lund University, Skåne University Hospital, Department of Clinical Sciences Lund, Rheumatology, Lund, Sweden

  • Department of Paediatrics, University of Cambridge, Cambridge, UK

Locations

  • Netherlands

  • United Kingdom

  • Spain

  • Germany

  • Switzerland

  • Ireland

  • France

  • Portugal

  • Sweden

  • Japan

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Nephrology

Disease

  • N/A

Biomarkers

  • C-C Motif Chemokine Ligand 2

  • Alpha-1 antitrypsin

  • B-lymphocyte antigen CD20

  • Nucleoside diphosphate kinase A

  • Cluster of Differentiation 163

  • Complement Component 5a

  • Protein Tyrosine Phosphatase, Non-Receptor Type 22

  • Proteinase 3

  • Cytotoxic T-lymphocyte-associated protein 4

  • Serpin A1

Drug/Treatment

  • Mycophenolate mofetil

  • CKD-4101

  • Hydroxychloroquine

  • Methylprednisolone

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • Glucocorticoid

  • Mycophenolic acid

  • Oraprine

  • Methotrexate

  • Prednisolone

  • Rituximab

  • CCX-168

  • Methadone hydrochloride

  • IdeS

Outcome

  • N/A


Study Design

  • Randomized

  • Placebo Control

  • Cross Over

  • Double Blind/Blinded

  • Open Label

  • Superiority

  • Non Inferiority

  • Multinational

  • Multicenteric

  • Prospective

  • Controlled

  • Cohort

Phase

  • III

Study Id's

  • NCT01731561

Sponsors

  • Medical Research Council (MRC)

Result

  • N/A