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: Association of changes in circulating cell-free plasma DNA (cfDNA) and circulating tumor cells (CTC) during treatment with clinical outcome from olaparib in castration-resistant prostate cancer (CRPC): Exploratory analyses from the TOPARP-A trial.

Researchers

Presenter

  • Joaquin Mateo

Principal Investigators

  • Jane Goodall

  • David Lorente

  • Nuria Porta

  • Suzanne Carreira

  • Susana Miranda

  • Zafeiris Zafeiriou

  • Christy Ralph

  • Suneil Jain

  • Robert J. Jones

  • Syed A. Hussain

  • Tony Elliott

  • Andrew Protheroe

  • Berni Ebbs

  • Lorna Leonard

  • Diletta Bianchini

  • Penelope Flohr

  • Emma Hall

  • Johann S. De Bono

Medical Centers

  • The Institute of Cancer Research & The Royal Marsden, London, Spain

  • Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, United Kingdom

  • Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom

  • Servicio Oncologia Medica Hospital Universitario La Fe, Valencia, Spain

  • Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, United Kingdom

  • St James's Institute of Oncology, St. James's University Hospital, West Yorkshire, United Kingdom

  • Queen's University Belfast, Belfast, United Kingdom

  • University of Glasgow, Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

  • University of Liverpool, Clatterbridge Cancer Centre NHS Foundation Trust, Wirral, United Kingdom

  • The Christie Hospital, Manchester, United Kingdom

  • Churchill Hospital, Oxford Medical Oncology Department, Oxford, United Kingdom

  • The Institute of Cancer Research, Sutton, United Kingdom

Locations

  • United Kingdom

  • Spain

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Nephrology

Disease

  • N/A

Biomarkers

  • Circulating tumor cells

  • Plasma cell-free DNA

Drug/Treatment

  • Olaparib

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • NCT01682772

Sponsors

  • N/A

Result

  • N/A

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