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963 : Artesunate Inhabits Migration and Invasion of Fibroblast-like Synoviocytes and Matrix Metalloproteinases Expression Via Suppression of PI3K/Akt Pathway in Rheumatoid Arthritis

Researchers

Presenter

  • Jian-Da Ma

Principal Investigators

  • Jun Jing

  • Tao Yan

  • Ying-Qian Mo

  • Lie Dai

Medical Centers

  • Department of Oncology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China

  • Zhongshan School of Medicine of Sun Yat-Sen University, Guangzhou, China

Locations

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • N/A

Biomarkers

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Pyruvate dehydrogenase kinase 1

  • Matrix metalloproteinase

Drug/Treatment

  • Hydroxychloroquine

  • Methotrexate

  • artesunate

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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