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: Unexpected Role of Adenosine-Monophosphate Activated Protein Kinase in Doxorubicin Cardiotoxicity and Metformin-Mediated Cardioprotection

Researchers

Presenter

  • Jaclyn Del Pozzo

Principal Investigators

  • Puja Mehta

  • Fei Cai

  • Cairong Li

  • Satoru Kobayashi

  • Qiangrong Liang

Medical Centers

  • New York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Endocrine/metabolic Diseases (ME)

  • Cardiovascular (CVS)

Disease

  • Type 2 diabetes mellitus

  • Cardiotoxicity

  • Diabetes

Biomarkers

  • AMP-activated protein kinase

  • Nucleoside diphosphate kinase A

  • Lactate dehydrogenase

  • Troponin I

Drug/Treatment

  • Doxorubicin

  • Adenosine

  • Adenosine Intravenous

  • Metformin Hydrochloride

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A