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: A Novel Gain of Function Variant of Prothrombin (p.R541W) Causes Dominant Heritable Thrombosis and Is Associated with Antithrombin Resistance

Researchers

Presenter

  • V. Muczynski

Principal Investigators

  • S. Sivapalaratnam

  • J. Collins

  • J. Pasi

  • A. Riddell

  • K. Downes

  • E. Turro

  • A.C. Nathwani

  • K. Gomez

Medical Centers

  • University College London Hospital, Department of Pathology, London, United Kingdom

  • The Royal Marsden Hospital, London, United Kingdom

  • University of Cambridge, Cambridge, United Kingdom

  • Queen Mary University of London, London, United Kingdom

  • The Royal Marsden Hospital NHS Foundation Trust, London & Surrey, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

  • Blood/haematological Diseases

  • Cardiovascular (CVS)

Disease

  • Venous thrombosis

Biomarkers

  • Alpha-tubulin N-acetyltransferase 1

  • Prothrombin

Drug/Treatment

  • Evithrom

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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