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12804 : HIF-1?/HuR Pathway Regulates the Increased Expression of PAI-1 Induced by Sphingosine 1-phosphate in HepG2 Cells Rendered Hypoxic: A Novel Linkage between Thrombosis and Hypoxia

Researchers

Presenter

  • Soichiro Iwaki

Principal Investigators

  • Moyoko Asai

  • Daisuke Sakakibara

  • Hiroaki Norimoto

  • Satoshi Fujii

Medical Centers

  • Nagoya City University, Nagoya, Japan

Locations

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Venous thrombosis

Biomarkers

  • Plasminogen activator ihnibitor-1

  • Hu antigen R

  • Hypoxia-inducible factor-1

  • Sphingosine-1-phosphate

  • Sphingosine-1-phosphate receptor 1

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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