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2414 : Genome-wide Association Analyses From The Vitamin Intervention For Stroke Prevention (visp) Trial Identify Genetic Loci That Influence Post-stroke Measures Of Inflammation And Thrombosis

Researchers

Presenter

  • Wei-Min Chen

Principal Investigators

  • Fang Chen

  • Bruce M Coull

  • Karen L Furie

  • Bradford B Worrall

  • Fang-Chi Hsu

  • Keith L Keene

  • Josyf C Mychaleckyj

  • Kimberly F Doheny

  • Corinne D Boehm

  • Cathy C Laurie

  • Stephanie Gogarten

  • Ebony B Bookman

Medical Centers

  • Massachusetts General Hospital, Boston, MA

  • University of Arizona, Tucson, AZ

  • University of Virgina, Charlottesville, VA

  • University of Washington, Seattle, WA

  • Natl Human Genome Res Inst, Bethesda, MD

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

Disease

  • Ischemic stroke

  • Venous thrombosis

  • Stroke

Biomarkers

  • Alpha-tubulin N-acetyltransferase 1

  • C reactive protein

  • Creatinine

  • TNF Alpha Induced Protein 1

  • von Willebrand factor

Drug/Treatment

  • Thrombomodulin alfa

  • FA-8

  • Evithrom

  • Lanthanum carbonate

Outcome

  • N/A


Study Design

  • randomized

  • double blind/blinded

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim