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16392 2014 AHA : Oxido-Reductive Regulation of Human Vascular Remodeling by the Orphan Receptor Tyrosine Kinase Ros1

Researchers

Presenter

  • Vinicio de Jesus Perez

Principal Investigators

  • Kimihiko Kato

  • Yoshiji Yamada

  • Mitsutoshi Oguri

  • Stanley L Hazen

  • J Wouter Jukema

  • Santhi K Ganesh

  • Elizabeth G Nabel

  • Keith Channon

  • Martin B Leon

  • Alain Charest

  • Mark Orcholski

  • Thomas Quertermous

  • Euan A Ashley

  • Stephen Pan

  • Wei Qi

  • Gaurav Chopra

  • Christopher Adams

  • Yoko Kojima

  • Nicholas J Leeper

  • Kathia Zaleta-Rivera

Medical Centers

  • Cleveland Clinic Fndn Learner Res Inst, Cleveland, OH

  • Brigham & Women's Hospital, Boston, MA

  • Columbia University, New York, NY

  • Tufts Univ Sch of Med, Medford, MA

  • Japanese Red Cross Nagoya First Hospital, Nagoya, Japan

  • University of Michigan Medical School, Ann Arbor, MI

  • University of Oxford, Oxford, United Kingdom

  • Leiden University Medical Centre, Leiden, Netherlands

  • MIe Univ, Mie, Japan

  • Stanford Univ. School of Med., Stanford, CA

Locations

  • United States

  • Japan

  • Netherlands

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Coronary Artery Disease

  • Venous thrombosis

Biomarkers

  • Protein Tyrosine Phosphatase, Non-Receptor Type 11

  • Proto-oncogene tyrosine-protein kinase ROS

  • Hepatocyte growth factor receptor

  • Glutathione

  • Glutathione peroxidase 1

Drug/Treatment

  • glutathione

  • Crizotinib

  • Cysteine Hydrochloride

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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