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14576 2014 BOS : Endogenous Superoxide Dismutase Protects From Impaired Generation of Activated Protein C and Enhanced Susceptibility to Experimental Thrombosis in Mice

Researchers

Presenter

  • Sean X Gu

Principal Investigators

  • Katinan M Wilson

  • Ryan Hutchins

  • Steven R Lentz

Medical Centers

  • University of Iowa, Iowa City, IA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Venous thrombosis

Biomarkers

  • Adenomatous Polyposis Coli

  • Nucleoside diphosphate kinase A

  • Superoxide dismutase

  • Superoxide dismutase 1

Drug/Treatment

  • Superoxide dismutase

  • Hydrogen peroxide

  • Thrombomodulin alfa

  • Fibrinogen (IV)

  • Protein C

  • Evithrom

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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