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P126 2015 HTN : Angiotensin II-induced Arterial Hypertension, Vascular Dysfunction and Inflammation is Promoted by Platelet-localized Coagulation Factor XI

Researchers

Presenter

  • Kerstin Jurk

Principal Investigators

  • Christoph Reinhardt

  • Karl Lackner

  • Brett Monia

  • Ulrich Walter

  • Zaverio Ruggeri

  • Thomas Renne

  • Wolfram Ruf

  • Thomas Munzel

  • Philip Wenzel

  • Tanja Schonfelder

  • Moritz Ehlken

  • Jeremy Lagrange

  • Maike Knorr

  • Moritz Brandt

  • Susanne Helena Karbach

  • Andreas Daiber

  • Matthias Oelze

Medical Centers

  • University Medical Center Mainz, Mainz, Germany

  • Karolinska Institutet, Stockholm, Sweden

  • The Scripps Res Inst, San Diego, CA

Locations

  • United States

  • Germany

  • Sweden

Companies

  • Isis Pharmaceuticals

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Vasodilation dysfunction

  • Pulmonary arterial hypertension

  • Venous thrombosis

  • Hypertension

Biomarkers

  • Vascular cell adhesion molecule 1

Drug/Treatment

  • Angiotensin II

  • Evithrom

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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