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607 2015 ATVB : Kininogen Regulates Thrombin Generation in a Mouse Model of Sickle Cell Disease

Researchers

Presenter

  • Kasemsiri Chandarajoti

Principal Investigators

  • Nigel S. Key

  • Andras Gruber

  • Nigel Mackman

  • Keith McCrae

  • Rafal Pawlinski

Medical Centers

  • Oregon Health and Science University, Portland, OR

  • Cleveland Clinic, Cleveland, OH

  • University of North Carolina, Chapel Hill, NC

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Sickle cell anemia

  • Venous thrombosis

Biomarkers

  • Alpha-tubulin N-acetyltransferase 1

  • Interleukin 6

  • Stearoyl-CoA desaturase

Drug/Treatment

  • rivaroxaban

  • Pradax

  • Evithrom

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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