// App-Quantinova.ai

P1-02-02 : mutations in circulating tumor cell versus circulating cell-free DNA of metastatic breast cancer patients before first-line endocrine therapy and at progression

Researchers

Presenter

  • AM Sieuwerts

Principal Investigators

  • N Beije

  • J Kraan

  • M Van

  • W Onstenk

  • SR Vitale

  • M van der Vlugt – Daane

  • P Hamberg

  • LY Dirix

  • A Brouwers

  • FE de Jongh

  • A Jager

  • CM Seynaeve

  • MPHM Jansen

  • JA Foekens

  • JWM Martens

  • S Sleijfer

Medical Centers

  • University of Catania, Italy

  • Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands

  • Sint Franciscus Gasthuis, Rotterdam, Netherlands

  • Ikazia Hospital, Rotterdam, Netherlands

  • Cancer Genomics Netherlands, Rotterdam, Netherlands

  • Oncology Center GZA Hospital Sint Augustinus, Translational Cancer Research Unit, Antwerp, Belgium

Locations

  • Belgium

  • Italy

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Breast cancer

Biomarkers

  • Circulating tumor cells

  • Estrogen Receptor 1

  • Plasma cell-free DNA

Drug/Treatment

  • Tamoxifen

Outcome

  • N/A


Study Design

  • pharmacodynamics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim