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P1-01-19 : Circulating tumor cells in triple-negative breast cancer patients express prostate related genes and show different genetic profiles in US and German patient cohorts

Researchers

Presenter

  • S Kasimir-Bauer

Principal Investigators

  • H Gao

  • A-K Bittner

  • L Plappert

  • N Feniuk

  • NT Ueno

  • L Cohen

  • V Valero

  • WA Woodward

  • RH Alvarez

  • O Hoffmann

  • R Kimmig

  • JM Reuben

Medical Centers

  • Integrative Medicine, Houston, TX

  • Breast Medical Oncology, Houston, TX

  • Hematopathology, Houston, TX

  • University Hospital of Essen, Essen, Germany

  • Radiation Oncology, Houston, TX

Locations

  • United States

  • Germany

Companies

  • Qiagen Hannover GmbH

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Urology

Disease

  • Triple-negative breast cancer

  • Prostate cancer

  • Breast cancer

Biomarkers

  • AKT Serine/Threonine Kinase 2

  • Anaplastic lymphoma Kinase

  • Neurogenic locus notch homolog protein 1

  • Aurora kinase A

  • Breast cancer type 1 susceptibility protein

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Circulating tumor cells

  • Poly(ADP-Ribose) Polymerase 1

  • Cluster of differentiation 45

  • Prostate specific antigen

  • Cytokeratin 5

  • Epidermal growth factor receptor

  • Epithelial Cell Adhesion Molecule

  • erb-b2 receptor tyrosine kinase 2

  • Erb-B2 Receptor Tyrosine Kinase 3

  • Excision repair cross-complementation group 1

  • Folate Hydrolase 1

  • Malondialdehyde

  • Serine/threonine-protein kinase mTOR

Drug/Treatment

  • Androgen Tear

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim