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135 : Daunorubicin or Not During the Induction Treatment of Childhood Standard-Risk B-Cell Precursor Acute Lymphoblastic Leukemia (SR-BCP-ALL): The Randomized Fralle 2000-A Protocol

Researchers

Presenter

  • Arnaud Petit

Principal Investigators

  • Caroline Thomas

  • Genevieve Margueritte

  • Christiane Vermylen

  • Odile Lejars

  • Isabelle Pellier

  • Claire Berger

  • Gerard Couillault

  • Catherine Paillard

  • Christian Berthou

  • Christophe Piguet

  • Gerard Michel

  • Brigitte Pautard

  • Jean so ULIER

  • Nathalie Grardel

  • Kheira Beldjord

  • Marie-Francoise Auclerc

  • Elizabeth Macintyre

  • Jean-Michel Cayuela

  • Sylvie Chevret

  • Guy Leverger

  • Yves Perel

  • Francoise Mechinaud

  • Virginie Gandemer

  • Claudine Schmitt

  • Pascale Schneider

  • Benoit Brethon

  • Anne Auvrignon

Medical Centers

  • Pediatric Hemato-Oncology, CHU Limoges, Limoges, France

  • Pediatric Hematology/Oncology, Univ. Hospital Amiens, Amiens, France

  • Hopital Necker-Enfants Malades, AP-HP and University Paris CNRS UMR, Paris, France

  • Dept. of Pediatric Hematology, Cliniques Universitaires Saint Luc, Brussels, Belgium

  • CHU Estaing, Centre de cancerologie et therapie cellulaire pediatrique INSERM CIC, Clermont-ferrand, France

  • Hopital Saint-Louis, AP-HP, Universite Paris , Paris, France

  • Service de Pediatrie et Hematologie Pediatrique, Hopital de la Timone Enfants, Marseille, France

  • Immuno-Hematologie-Oncologie Pediatrique, CHU, Dijon, France

  • hopital Trousseau, hematologie et oncologie pediatrique, Paris, France

  • Immuno-Hematologie Pediatrique, CHU, Rouen, France

  • Dept. of Pediatric Hematology, Robert Debre hospital, APHP, Paris, France

  • Pediatric Oncology, Hopital Trousseau, Paris, France

  • CHRU Lille, Universite Lille, Lille, France

  • Pediatric Hematology and Oncology Department, Trousseau Hospital - APHP and UPMC Univ Paris 06, Paris, France

  • Centre Hayem, Hopital S Louis, Paris, France

  • Pediatric Hematology Unit, CHU Bordeaux, Bordeaux, France

  • CHU Montpellier pediatrie, Montpellier, France

  • Department of Pediatric Hematology-Immunology, Robert Debre Hospital, Paris, France

  • Pediatric Oncology, University Hospital, Lille, France

  • Pediatric Hematology,, Hopital Robert Debre, paris,

  • Rheumatology, University Hospital, Lille, France,

  • Pediatric Hematology Oncology, CHU de Nancy, Vandoeuvre, France,

  • Laboratoire Central -Hematologie, Hopital Saint-Louis, Paris, France

Locations

  • France

  • Belgium

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Acute lymphoblastic leukemia

  • Down syndrome

  • Pancreatitis

  • Glioblastoma

  • Venous thrombosis

Biomarkers

  • ETV6-RUNX1

  • Histone-lysine N-methyltransferase 2A

  • White Blood Cell

  • T-cell receptor

Drug/Treatment

  • Allmercap

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Daunorubicin

  • Methotrexate

  • Asparaginase

  • Vincristine

  • Doxorubicin

  • Prednisone

  • 6-mercaptopurine

Outcome

  • N/A

Study Design

  • randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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