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104 : Kininogen Deficiency Protects From Ischemic Neurodegeneration in Mice by Reducing Thrombosis, Blood-Brain-Barrier Damage and Inflammation

Researchers

Presenter

  • Eva Gob

Principal Investigators

  • Peter Kraft

  • Guido Stoll

  • Sven G Meuth

  • Bernhard Nieswandt

  • Keith R. McCrae

  • Christoph Kleinschnitz

  • Christian Geis

  • Joachim Schmitt

  • Marc Brede

  • Kirsten Gobel

  • Xavier Helluy

  • Mirko Pham

  • Martin Bendszus

  • Peter Jakob

Medical Centers

  • Physiology, University of Wuerzburg, Wuerzburg, Germany

  • Experimental Physics, University of Wurzburg, Wurzburg, Germany

  • University Clinic Heidelberg, Heidelberg, Germany

  • Neurology and Neuropathophysiology, University of Munster, Munster, Germany

  • Rudolph Virchow Center, DFG Research Center for Experimental Biomedicine, Wurzburg, Wurzburg, Germany,

  • Institute of Pharmacology and Toxicology, University of Wuerzburg, Germany

  • Anesthesiology and Critical Care, University of Wurzburg, Wurzburg, Germany

  • Neurology-Inflammatory Disorders and Neurooncology, University of Munster, Munster, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

Disease

  • Ischemic stroke

  • Ischemic injury

  • Venous thrombosis

  • Stroke

Biomarkers

  • Interleukin 1

Drug/Treatment

  • Rose bengal sodium

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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