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386 : 2-O, 3-O-Desulfated Heparin (ODSH) Mitigates Chemotherapy-Induced Thrombocytopenia (CIT) by Blocking the Negative Paracrine Effect of Platelet Factor 4 (PF4) On Megakaryopoiesis

Researchers

Presenter

  • Samriddhi S Sharma

Principal Investigators

  • Liqing Xiao

  • Stephen Marcus

  • Mortimer Poncz

Medical Centers

  • Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA

Locations

  • United States

Companies

  • ParinGenix Inc.

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Thrombocytopenia

  • Acute lymphoblastic leukemia

  • Metastatic pancreatic adenocarcinoma

  • Pancreatic cancer

  • Solid malignancies

Biomarkers

  • Platelet Factor 4

Drug/Treatment

  • Heparin

  • Adrucil injection

  • ODSH

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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