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379 : Polo-Like Kinase 3, a Novel Regulator of Thrombosis: Positive Regulation of TxA2 Generation, Granular Secretion and Clot Retraction, but Negative Regulation of Integrin Activation

Researchers

Presenter

  • Brendan Bachman

Principal Investigators

  • John C Kostyak

  • Wei Dai

  • Ulhas P Naik

Medical Centers

  • N/A

Locations

  • N/A

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Venous thrombosis

Biomarkers

  • Mitogen-activated protein kinase 1

  • Mitogen-activated protein kinase 3

  • Phosphatase and tensin homolog

  • Polo-like kinase 1

Drug/Treatment

  • Epinephrine

  • Adrenaclick

  • Fibrinogen (IV)

  • Evithrom

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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