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106 : ?2-Glycoprotein 1 Antibodies Directly Activate the Platelet IgG Receptor, Fc?RIIa, and Cause Thrombosis in FCGR2A Transgenic but Not in Wild Type Mice

Researchers

Presenter

  • Todd V Meyer

Principal Investigators

  • Liza Robles-Carrillo

  • Meghan Hatfield

  • Hina Desai

  • Mildred Amaya

  • Florian Langer

  • Steven E. McKenzie

  • John L Francis

Medical Centers

  • Hubertus Wald University Cancer Center Department of Oncology and Hematology, University Medical Center Eppendorf, Hamburg, Germany

  • Center for Thrombosis Research, Florida Hospital, Orlando, FL

Locations

  • United States

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Antiphospholipid syndrome

  • Thrombocytopenia

  • Venous thrombosis

Biomarkers

  • Immunoglobulin G

  • Vascular endothelial growth factor A

Drug/Treatment

  • Heparin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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