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126 : Exome Sequencing and Ultra-Deep Sequencing of Paired Diagnosis, Remission and Relapse Samples Reveals the Clonal Diversity and Treatment-Induced Evolution of Childhood Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Simon V. van Reijmersdal

Principal Investigators

  • Marc M Hahn

  • Edwin Sonneveld

  • Peter M. Hoogerbrugge

  • Ad Geurts van Kessel

Medical Centers

  • Dutch Childhood Oncology Group, The Hague, Netherlands.

  • Department of Urology, Radboud University Medical Center, Nijmegen, Netherlands

  • Experimential Rheumatology, Radboud university medical center, Nijmegen, Netherlands

Locations

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Paired box 5

  • T-cell receptor

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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