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302 : Sequential High Dose Immuno-Chemotherapy Followed by Autologous Peripheral Blood Stem Cell Transplantation for Patients with Untreated Primary Central Nervous System Lymphoma - a Multicentre Study by the Collaborative PCNSL Study Group Freiburg

Researchers

Presenter

  • Kristina Fritsch

Principal Investigators

  • Norbert Frickhofen

  • Martin Bentz

  • Alexander Roeth

  • Robert Mohle

  • Tobias Birnbaum

  • Michael Pfreundschuh

  • Claudia Hader

  • Gabriele Ihorst

  • Martina Deckert

  • Marco Prinz

  • Monika Lamprecht

  • Elisabeth Schorb

  • Heidi Fricker

  • Benjamin Kasenda

  • Jurgen Finke

  • Nikolas von Bubnoff

  • Hans-Heinrich Wolf

  • Gottfried Dolken

  • Stephan Stilgenbauer

  • Jens Panse

  • Stefan Balabanov

  • Peter Hau

Medical Centers

  • Dept of Medicine, Haematology&Oncology, Freiburg University Medical Center, Freiburg, Germany

  • Department of Dermatology, University Hospital, Cologne, Germany

  • Dept of Medicine, Haematology&Oncology, Freiburg University Medical Center, Freiburg, Germany

  • Hematology/Oncology, University Hospital Aachen, Aachen, Germany

  • Klinik fuer Innere Medizin C und Poliklinik, University Greifswald, Greifswald, Germany

  • Ulm University, Department of Internal Medicine I, Ulm, Germany

  • Haematology/Oncology, University Hospital Medical Center, Kiel, Germany

  • Innere Medizin I, Universitaetsklinikum des Saarlandes, Homburg/Saar, Germany

  • Dept. of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany

  • Clinical Trials Unit, University Medical Center, Freiburg, Germany

  • Klinik fur Onkologie, Hamatologie und Knochenmarktransplantation mit Sektion Pneumologie, Universitats-Klinikum Hamburg-Eppendorf, Hamburg, Germany

  • Department of Internal Medicine III, Klinikum Karlsruhe, Karlsruhe, Germany

  • University of Duisburg-Essen, Essen, Germany

  • Haematology, University of Freiburg, Freiburg, Germany,

  • Hematology / Oncology, HSK, Dr.-Horst-Schmidt-Klinik, Wiesbaden, Germany

  • Medical Department, Hematology and Oncology, University of Tuebingen, Tuebingen, Germany

  • Hematology, University Hospital Halle, Halle, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Primary central nervous system lymphoma

  • Non-Hodgkin's Lymphoma

  • CNS lymphoma

  • Hodgkin's Lymphoma

  • B cell lymphomas

  • T-cell lymphoma

  • Renal insufficiency

  • Pulmonary alveolar proteinosis

  • Non‐Hodgkin Lymphoma

  • Lymphomas

Biomarkers

  • Circulating tumor cells

Drug/Treatment

  • Methotrexate

  • Carmustine

  • Cytarabine liposomal

  • Rituximab

  • Thiotepa

  • Recombinant granulocyte colony-stimulating factor

Outcome

  • N/A

Study Design

  • randomized

Phase

  • NA

Study Id's

  • NCT00647049

Sponsors

  • N/A

Result

  • Interim

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