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144 : Sorafenib Versus Placebo in Addition to Standard Therapy in Adult Patients ?60 Years with Newly Diagnosed Acute Myeloid Leukemia: Results From the Randomized-Controlled Soraml Trial

Researchers

Presenter

  • Carsten Muller-Tidow

Principal Investigators

  • Aristoteles Giagounidis

  • Walter E. Aulitzky

  • Martin Bornhauser

  • Markus Schaich

  • Stefani Parmentier

  • Christian Thiede

  • Malte von Bonin

  • Thomas Illmer

  • Johannes Schetelig

  • Michael Kramer

  • Volker Kunzmann

  • Hubert Serve

  • Wolfgang E Berdel

  • Gerhard Ehninger

  • Claudia D Baldus

  • Christian H. Brandts

  • Alwin Kramer

  • Kerstin Schafer-Eckart

  • Andreas Neubauer

  • Stefan W. Krause

  • Utz Krug

Medical Centers

  • Department of Medicine A / Hematology and Oncology, University of Muenster, Muenster, Germany

  • Department of Medicine A / Hematology and Oncology, University of Muenster, Muenster, Germany

  • Dep. of Hematology/Oncology and Immunology, University Hospital Marburg, Marburg, Germany

  • Universitatsklinikum Carl Gustav Carus, Medizinische Klinik und Poliklinik I, Dresden, Germany

  • Hematology, University Hospital, Essen, Germany

  • Department of Medicine, Hematology/Oncology, Goethe University of Frankfurt, Frankfurt, Germany

  • Department of Internal Medicine II, Hematology and Oncology, Goethe University Hospital, Frankfurt, Germany

  • Medizinisch e Klinik und Poliklinik I, Universitaetskinikum Dresden, Dresden, Germany

  • Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany

  • Innere Klinik II, Robert-Bosch-Krankenhaus, Stuttgart, Germany

  • Medizinische Klinik und Poliklinik II, Julius Maximilians Universitat Wurzburg, Wurzburg, Germany

  • Dept. of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany

  • Department of Internal Medicine I, University Hospital TU Dresden, Dresden, Germany

  • Medizinische Klinik 5, Universitaetsklinikum Erlangen, Erlangen, Germany

  • Medizinische Klinik 5, Klinikum Nuernberg Nord, Nuernberg, Germany

  • Department of Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany

  • Department of Hematology and Oncology, Charite, University Hospital Berlin, Campus Benjamin Franklin, Berlin, Germany

  • Medizinische Klinik II, St. Johannes Hospital, Duisburg, Germany

  • DFG - Collaborative Research Centre , SFB , Dresden, Germany

  • Medizinische Klinik und Poliklinik I, Universitaetsklinikum Carl Gustav Carus der TU Dresden, Dresden,

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Acute myelocytic leukemia

  • Hypertension

Biomarkers

  • Circulating tumor cells

Drug/Treatment

  • Daunorubicin

  • Mitoxantrone

  • Cytarabine liposomal

  • Sorafenib

Outcome

  • N/A

Study Design

  • randomized

  • double blind/blinded

Phase

  • NA

Study Id's

  • NCT00893373

Sponsors

  • N/A

Result

  • Interim

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