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880 : Leukemia Cells with a BCR-ABL1-Like signature and/or IKZF1 deletions, but Not High CRLF2 Expression, Are Predictive of an Unfavorable Prognosis in Childhood B Cell Precursor Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Esmee Waanders

Principal Investigators

  • Rob Pieters

  • G. Escherich

  • Martin Horstman

  • Leila mohammadi Khankahdani

  • Dimitris Rizopoulos

  • Hester A. de Groot-Kruseman

  • Edwin Sonneveld

  • Roland P. Kuiper

  • Monique L. den Boer

  • Marieke E. Willemse

  • Simon Reijmersdaal

  • Lisa J Russell

  • Christine J Harrison

  • William E. Evans

  • Vincent H.J. van der Velden

  • Peter M. Hoogerbrugge

  • Frank N. van Leeuwen

Medical Centers

  • Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom

  • German Cooperative Study Group for Childhood Acute Lymphoblastic Leukemia, Hamburg, Germany

  • Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands

  • Dutch Childhood Oncology Group, The Hague, Netherlands.

  • ErasmusMC - department of biostatistics, Rotterdam, Netherlands

  • Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands

  • Department of Urology, Radboud University Medical Center, Nijmegen, Netherlands

  • Department of Clinical Pharmacy, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands

  • Department of Immunology, Erasmus Medical Center, Rotterdam, Netherlands

Locations

  • Germany

  • United Kingdom

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • ETV6-RUNX1

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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