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878 : Genome-Wide Association Study Identifies Germline Polymorphisms Associated with Relapse of Childhood Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Cheng Cheng

Principal Investigators

  • Naomi Winick

  • Paul L. Martin

  • W. Paul Bowman

  • Bruce Camitta

  • Gregory Reaman

  • William L. Carroll

  • Cheryl L Willman

  • Stephen P. Hunger

  • William E. Evans

  • Ching-Hon Pui

  • Xueyuan Cao

  • Mignon L. Loh

  • Mary V. Relling

  • Dario Campana

  • Wenjian Yang

  • Yiping Fan

  • Geoffrey A.M. Neale

  • Nancy Cox

  • Paul Scheet

  • Michael J. Borowitz

Medical Centers

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • ETV6-RUNX1

  • Histone-lysine N-methyltransferase 2A

  • DNA index

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Methotrexate

  • Asparaginase

  • Prednisone

Outcome

  • N/A

Study Design

  • pharmacokinetics

  • pharmacodynamics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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