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874 : Identification of FoxM1 As Therapeutic Target in TKI-Resistant Ph+ ALL

Researchers

Presenter

  • Lars Klemm

Principal Investigators

  • Chen Zhengshan

  • Huimin Geng

  • Markus Muschen

Medical Centers

  • N/A

Locations

  • N/A

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Liver cancer

  • Breast cancer

  • Solid malignancies

  • Lymphomas

  • Philadelphia chromosome–positive (Ph+) ALL

Biomarkers

  • Breakpoint Cluster Region

  • Ph chromosome

  • Cluster of Differentiation 19

  • Cyclin Dependent Kinase Inhibitor 2A

Drug/Treatment

  • Superoxide dismutase

  • Thiostrepton

  • Tamoxifen

  • Imatinib

  • IkT001

  • L-Tyrosine

  • Afimoxifene

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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