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692 : Dissecting the Complexity of Philadelphia-Positive Mutated Populations by Ultra-Deep Sequencing of the Bcr-Abl Kinase Domain: Biological and Clinical Implications

Researchers

Presenter

  • Caterina De Benedittis

Principal Investigators

  • Federica Cattina

  • Paola Bresciani

  • Valeria Coluccio

  • Marzia Salvucci

  • Mario Tiribelli

  • Gianni Binotto

  • Tamara Intermesoli

  • Mario Luppi

  • Maria Teresa Bochicchio

  • Emanuela Ottaviani

  • Adela Brouckova

  • Domenico Russo

  • Gianantonio Rosti

  • Michele Baccarani

  • Giovanni Martinelli

  • Fausto Castagnetti

  • Cristina Papayannidis

  • Gabriele Gugliotta

  • Francesca Palandri

  • Hana Klamova

  • Ilaria Iacobucci

  • Claudia Venturi

Medical Centers

  • Hematology, Ospedale Santa Maria delle Croci, Ravenna, Italy

  • Hematology, University of Brescia, Brescia, Italy

  • Department of Clinical and Experimental Medicine, Hematology Section, Padua University School of Medicine, Padova, Italy

  • Division of Hematology and Bone Marrow Transplantation, Department of Experimental and Clinical Medical Sciences, AOU Udine, University of Udine, Udine, Italy

  • Department of Hematology/Oncology, University of Bologna, Bologna, Italy

  • Institute of Hematology and Blood Transfusion, Prague, Czech Republic

  • Bone Marrow Transplant Unit, Department of Oncology and Hematology, University of Modena, Modena, Italy

  • Division of Hematology, Ospedali Riuniti, Bergamo, Italy

Locations

  • Czech Republic

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Chronic Myelogenous Leukemia

Biomarkers

  • Breakpoint Cluster Region

Drug/Treatment

  • Nilotinib

  • Ponatinib

  • dasatinib

  • Imatinib

  • IkT001

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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