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665 : Effects of Dexamethasone (DEX) Vs Prednisone (PDN) and High-Dose Methotrexate (HD-MTX) Vs Capizzi Methotrexate/Asparaginase (C-MTX/ASNase) On Osteonecrosis (ON) Incidence in Children and Young Adults with High Risk Acute Lymphoblastic Leukemia (HR-ALL): A Report From the Children's Oncology Group (COG) Study AALL0232

Researchers

Presenter

  • Meenakshi Devidas

Principal Investigators

  • Naomi Winick

  • Elizabeth Raetz

  • Stephen P. Hunger

  • William L. Carroll

  • Eric C. Larsen

Medical Centers

  • New York University Medical Center, New York City, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Nucleoside diphosphate kinase A

  • Hormone receptor

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Methotrexate

  • Pegaspargase

  • Oncaspar

  • Asparaginase

  • Prednisone

Outcome

  • N/A


Study Design

  • randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim