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635 : Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

Researchers

Presenter

  • Hyun Sook Ahn

Principal Investigators

  • Rudy Fuentes

  • Vincent M. Hayes

  • Sergei V. Zaytsev

  • X. Long Zheng

  • Douglas B. Cines

  • Steven E. McKenzie

  • John W. Weisel

  • Mortimer Poncz

  • Lubica Rauova

Medical Centers

  • Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Thrombocytopenia

  • Venous thrombosis

Biomarkers

  • Platelet Factor 4

  • Spleen tyrosine kinase

  • von Willebrand factor

Drug/Treatment

  • Fibrinogen (IV)

  • PRT060318

  • Evithrom

  • L-Tyrosine

  • Heparin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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