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4307 : A Phase II Trial of Decitabine and Vorinostat in Combination with Chemotherapy for Relapsed/Refractory Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Jatinder Lamba

Principal Investigators

  • Brenda Weigel

  • Veronika Bachanova

  • Michael R. Verneris

  • Jeffrey S. Miller

Medical Centers

  • Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota Masonic Cancer Center, Minneapolis, MN

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

Drug/Treatment

  • PEG-asparaginase

  • Vincristine

  • Doxorubicin

  • Decitabine

  • Prednisone

  • Vorinostat

Outcome

  • N/A

Study Design

  • pharmacodynamics

Phase

  • NA

Study Id's

  • NCT00882206

Sponsors

  • N/A

Result

  • Interim

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