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4293 : High Dose Cytarabine and Mitoxantrone in Combination with Dasatinib As Active Induction Therapy in Adult Patients with Philadelphia Chromosome Positive (ph+) Acute Lymphoblastic Leukemia (ALL)

Researchers

Presenter

  • Mark Weiss

Principal Investigators

  • Ellin Berman

  • Mark G. Frattini

  • Mark Heaney

  • Joseph G. Jurcic

  • Todd L. Rosenblat

  • Heather Landau

  • Hanna Weissbrot

  • Peter G. Maslak

Medical Centers

  • Lymphoma Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Philadelphia chromosome–positive (Ph+) ALL

Biomarkers

  • Breakpoint Cluster Region

  • Ph chromosome

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Mitoxantrone

  • Vincristine

  • Cytarabine liposomal

  • Prednisone

  • Nilotinib

  • dasatinib

  • Imatinib

  • IkT001

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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