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1474 : Frequency and Clinical Presentation of Polycomb Repressive Complex 2 (PRC2) Component Mutations in Childhood Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Vivien Schafer

Principal Investigators

  • Jenny Rinke

  • Anja Waldau

  • Susan Wittig

  • Jana Ernst

  • Ralf Hafer

  • James F Beck

  • Andreas Hochhaus

  • Bernd Gruhn

Medical Centers

  • Klinik fur Innere Medizin II, Universitatsklinikum Jena, Jena, Germany

  • Klinik fur Kinder und Jugendmedizin, Universitatsklinikum Ulm, Ulm, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Polycomb repressive complex 2

  • Embryonic ectoderm development

  • Enhancer of zeste homolog 2

Drug/Treatment

  • EZH2

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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