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1473 : Two Years Follow-up Results of Graspall/Graall-SA22008 Study: L-Asparaginase-Loaded Red Blood Cell Combined with Standard EWALL Chemotherapy in Older Patients with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia (Ph-ALL)

Researchers

Presenter

  • Mathilde Hunault-Berger

Principal Investigators

  • Françoise Huguet

  • Stéphane Leprêtre

  • Eric Deconinck

  • Mario Ojeda Uribe

  • Caroline Bonmati

  • Pierre Bories

  • Chantal Himberlin

  • Patrice Chevallier

  • Philippe Rousselot

  • Oumedaly Reman

  • Marie-Laure Boulland

  • Severine Lissandre

  • Pascal Turlure

  • Didier Bouscary

  • Laurence Sanhes

  • Ollivier Legrand

  • Isabelle Plantier

  • Frédérique Orsini Piocelle

  • Véronique Lhéritier

  • Elodie Boucher

  • Yann Godfrin

  • Norbert Ifrah

  • Hervé Dombret

Medical Centers

  • CHU Nantes, Nantes, France

  • Hematology, CHU, Angers, France

  • Hopital Hautepierre, Strasbourg, France

  • Hopital de Roubaix, France,

  • CHU Robert Debre, Reims, France

  • Hematology, Hopital Purpan, Universite Toulouse, Toulouse, France

  • Hematology, CH, Perpignan, France

  • Hopital Sud, Universite Rennes, Rennes, France

  • CHRU de Tours, Tours, France

  • CHU Caen, Universite Caen, Caen, France

  • Hospital Saint Antoine, Paris, France

  • CHU Dupuytren, Universite Limoges, Limoges, France

  • Hopital Haut-Leveque, Universite Bordeaux, Pessac, France

  • Hopital Jean Minjoz, Besancon, France

  • CHU, Angers, France

  • Hopital Edouard Herriot, Lyon, France

  • Hopital Cochin, Paris, France

  • CH Annecy, Pringy, France,

  • Hopital de Brabois Adultes, Vandoeuvre-Les-Nancy, France

  • GRAALL Coordination Center, Centre Hospitalier Lyon Sud, Pierre Benite, France

  • CH Mulhouse, Mulhouse, France

  • Hopital Mignot, Le Chesnay, France

  • Hematologie, Centre Henri Becquerel, Rouen, France

  • Hopital Saint-Louis, AP-HP, Universite Paris , Paris, France

Locations

  • France

Companies

  • Erytech Pharma Inc.

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Philadelphia chromosome–positive (Ph+) ALL

Biomarkers

  • Red Blood Cells

  • T-cell receptor

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • Allmercap

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Methotrexate

  • Asparaginase

  • Vincristine

  • Cytarabine liposomal

  • Graspa

Outcome

  • N/A

Study Design

  • open label

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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