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1468 : YB-1 Is Activated by IL-7 and Is Overexpressed in Pediatric Pre-B Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Sabine M Ivison

Principal Investigators

  • Vivian Leung

  • Sandra E. Dunn

  • Aru Narendran

  • Erwin T Cabacungan

  • Kirk R. Schultz

Medical Centers

  • Div. Pediatric Hem./Onc./ BMT, Child and Family Research Institute, Vancouver, BC, Canada,

  • Div. Pediatric Hem./Onc./ BMT, Child and Family Research Institute, Vancouver, BC, Canada,

  • Southern Alberta Cancer Research Institute, University of Calgary, Calgary, AB, Canada

  • Child and Family Research Institute, Vancouver, BC, Canada

  • Oncology Research Program - CFRI, B.C. Children's Hospital, Vancouver, BC, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B cell lymphomas

  • Lymphomas

Biomarkers

  • Mitogen-activated protein kinase

  • Dual specificity mitogen-activated protein kinase kinase 1

  • B-lymphocyte antigen CD20

  • Breakpoint Cluster Region

  • Peripheral blood mononuclear cell

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Cluster of Differentiation 19

Drug/Treatment

  • Efaproxiral

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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