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1499 : Identification of Sphingosine Kinases As Therapeutic Targets in B-Lineage Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Kenneth F Bradstock

Principal Investigators

  • Linda J Bendall

Medical Centers

  • Westmead Hospital, Sydney, Australia

Locations

  • Australia

Companies

  • Millennium Pharmaceu

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of Differentiation 19

  • Cluster of differentiation 45

  • DNA Damage Inducible Transcript 3

  • Sphingosine-1-phosphate

Drug/Treatment

  • ABC294640

  • Imatinib

  • IkT001

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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