// App-Quantinova.ai

1616 : Single Nucleotide Polymorphisms in ABCB1 and CBR1 Predict Toxicity to R-CHOP Type Regimens in Patients with Diffuse Non Hodgkin's Lymphoma

Researchers

Presenter

  • Vincent Ribrag

Principal Investigators

  • Herve Ghesquieres

  • Sophie Pallardy

  • Richard Delarue

  • Herve Tilly

  • Corinne Haioun

  • Fabrice Jardin

  • Gilles Salles

  • Charles Dumontet

Medical Centers

  • Hematologie UMR CNRS, Centre Hospitalier Universitaire Lyon-Sud, Lyon, France

  • Hematologie, Centre Henri Becquerel, Rouen, France

  • Hospices Civils De Lyon, Pierre Benite, France

  • UMR , ProfilExpert, Lyon, France

  • CRLCC Henri Becquerel, Rouen, France

  • Laboratory of Hematology, Lyon Sud Hospital, Pierre Benite, France

  • Hematology, Hopital Henri Mondor, Creteil Cedex, France

  • Institut Gustave-Roussy, Villejuif, France

  • Onco-dermatology unit, Centre Leon Berard, Lyon, France

  • Nephrology, Necker Hospital, Paris, France

Locations

  • France

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Diffuse large B-cell lymphoma

  • Hodgkin's Lymphoma

  • Thrombocytopenia

  • B cell lymphomas

  • Non‐Hodgkin Lymphoma

  • Lymphomas

  • Anemia

Biomarkers

  • ATP Binding Cassette Transporter B1

  • Catalase

  • Circulating tumor cells

  • Cytochrome P450 Family 3 Subfamily A Member 4

  • Fibroblast growth factor receptor 4

  • Glutathione S-Transferase Mu 1

  • Glutathione S-transferase P1

  • Glutathione S-Transferase Theta 1

  • Human albumin

  • Interleukin 10

  • UDP glucuronosyltransferase family 1 member A1

Drug/Treatment

  • Doxorubicin

  • Interleukin-10

Outcome

  • N/A

Study Design

  • randomized

  • pharmacokinetics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

Copyright © 2026. QuantiNova All rights reserved