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1361 : Triggering of CD44 by Ultra-Low-Molecular-Weight Hyaluronan Induces Cell Death by Autophagy Via Endoplasmic Reticulum Stress in Acute Lymphoblastic Leukemia with MLL Gene Rearrangements

Researchers

Presenter

  • Yoshiyuki Furuichi

Principal Investigators

  • Norie Ando

  • Keiko Kagami

  • Kumiko Goi

  • Takeshi Inukai

  • Kanji Sugita

Medical Centers

  • Life Science Special Course, University of Yamanashi, Chuo, Yamanashi, Japan

  • Pediatrics, School of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan

Locations

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

Biomarkers

  • Annexin V

  • Breakpoint Cluster Region

  • High Mobility Group Box 1

  • Histone-lysine N-methyltransferase 2A

  • Hyaluronic acid

Drug/Treatment

  • Hyaluronic acid

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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