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1274 : Immunoglobulin Heavy Chain Locus (IGH@) Translocations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Incidence and Risk Stratification

Researchers

Presenter

  • Lisa Jones

Principal Investigators

  • Amy Erhorn

  • Amir Ensahei

  • Dino Masic

  • Helen Bentley

  • Karl S Laczko

  • Christine J Harrison

Medical Centers

  • Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom

  • Leica Microsystems, Gateshead, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B cell lymphomas

  • Solid malignancies

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • B-cell lymphoma 2

  • Paired box 5

  • CCAAT enhancer binding protein alpha

  • CCAAT enhancer binding protein delta

  • CCAAT enhancer binding protein gamma

  • Cyclin Dependent Kinase Inhibitor 2A

  • Cyclin Dependent Kinase Inhibitor 2B

  • Retinoblastoma protein

  • ETV6-RUNX1

  • Immunoglobulin heavy-chain variable region gene

  • T cell receptor alpha locus

  • TAL BHLH Transcription Factor 1, Erythroid Differentiation Factor

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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